Best Non Toxic Hand Lotion

Last Updated on March 21, 2025 by NonToxicSwaps

Switch to a safer, non toxic hand lotion and eliminate unhealthy ingredients from your moisturizer.

The purpose of using hand lotion is to soften and moisturize the skin. It should be healing and nourishing, however, many brands on the market can contain ingredients that can bioaccumulate and/or add to your overall exposure to toxic ingredients.

Fortunately, there are safer options to choose from. In this post, I’m sharing the best non toxic hand lotions so you can eliminate this as a source of unsafe ingredients from your daily toxic load.

Table of Contents

Ingredients to Avoid

Hand lotion can be made up of concerning ingredients. Ingredients to avoid when searching for a non toxic hand lotion are:

Fragrance/Parfum: umbrella term including hundreds of toxins, including hormone disrupting phthalates, as well as skin irritants and allergens. Chemicals that are hidden behind this term can be carcinogenic, respiratory irritants, endocrine disruptors, reproductive toxins, neurotoxins, and more (PMID: 35669814)
Parabens: preservatives linked to endocrine disruption (PMID: 29596967), known to be carcinogenic due to endocrine disruption (PMID: 36746253) Parabens may be listed as methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, isopropylparaben, and benzylparaben.
Ethoxylated ingredients (PEGs, PPGs, polysorbates, ceteareth, phenoxyethanol): ethoxylation process produces ethylene oxide, a carcinogen and developmental toxin (PubChem CID: 6354) and 1,4-dioxane, a suspected carcinogen (PubChem CID: 31275)
Phenoxyethanol: deemed generally safe at a 1% concentration, however it’s production process, ethoxylation, can potentially contaminate phenoxyethanol with 1,4-dioxane and ethylene oxide (see above for ethoxylated ingredient description) (PubChem CID: 31236)
Polyquaterniums: (aka “quats”) group of polymers that may release formaldehyde and produce nitrosamines, both of which are known carcinogens (PubChem CID: 6433396)
Potassium sorbate: skin, eye, respiratory irritant, (PubChemID: 23676745); caused DNA damage when combined with ascorbic acid and Fe-salt (PMID: 12176085) and deemed genotoxic to human lymphocytes by this study (PMID: 20036729)
Sodium benzoate: study has shown to be mutagenic and cytotoxic in lymphocytes (PubChem ID: 517055); can form benzene when combined with ascorbic acid (Vitamin C) (PMID: 33371618)